Top HIPAA-Compliant Cloud Storage for Healthcare 2025
Introduction to HIPAA-Compliant Cloud Storage in 2025
In the digital age of healthcare, electronic health records (EHRs) and protected health information (PHI) are essential for patient care, but cybersecurity threats loom large. The IBM Cost of a Data Breach Report 2024 reveals that healthcare experienced the highest average breach costs for the 14th year running, reaching $9.77 million per incident—the highest in the U.S.—almost double the global average of $4.88 million. This marks a 10% rise from 2023, the biggest jump since the pandemic, fueled by operational disruptions, customer loss, and hefty regulatory fines. Breaches now take 291 days on average to resolve, amplifying risks for organizations storing sensitive medical data in the cloud.
As 2025 unfolds, cloud adoption for EHRs, telemedicine, and remote monitoring surges with hybrid work and AI diagnostics. Healthcare providers are shifting vast amounts of PHI to cloud platforms for efficiency and access. Yet, this shift amplifies vulnerabilities: cloud misconfigurations drove 15% of 2024 breaches, while shadow data in hybrid setups contributed to 40% of cases, costing over $5 million each and taking 283 days to contain.
This guide details the best HIPAA-compliant cloud storage solutions for 2025, assessing them on security, integration ease, and value. We break down HIPAA basics, must-have features, leading providers, comparisons, and trends to empower healthcare decision-makers in safeguarding PHI and driving innovation.
Article Overview: - HIPAA compliance essentials for cloud storage - Critical features for secure medical data handling - Top HIPAA-compliant cloud storage providers ranked for 2025 - Head-to-head comparison of options - Implementation strategies and 2025 trends
$9.77M
Average cost of a healthcare data breach in 2024 (IBM Cost of a Data Breach Report)

Understanding HIPAA Compliance for Cloud Storage in Healthcare
The Health Insurance Portability and Accountability Act (HIPAA) of 1996 sets U.S. standards for securing healthcare data. Its Privacy Rule safeguards PHI confidentiality—covering identifiable details like medical histories, diagnoses, and billing—while the Security Rule mandates safeguards for electronic PHI (ePHI) across administrative, physical, and technical domains. These apply to covered entities (e.g., hospitals, clinics, insurers) and business associates like cloud providers managing PHI.
Cloud storage introduces unique risks as data leaves on-site servers, including unauthorized access, transmission leaks, or phishing attacks, which caused 15% of 2024 breaches at $4.76 million average cost. Noncompliance penalties are severe: up to $50,000 per violation, with cumulative HIPAA fines surpassing $6.5 billion recently. Willful violations can lead to criminal charges, jail time, and lasting damage to patient trust.
Central to compliance is the Business Associate Agreement (BAA), a binding contract outlining PHI handling, 60-day breach notifications, and secure disposal. No BAA means no legal PHI storage. Providers like AWS and Azure offer standard BAAs; others may need custom talks.
For 2025, HIPAA evolves against modern threats. The U.S. Department of Health and Human Services (HHS) on January 6, 2025, proposed Security Rule updates to enhance ePHI cybersecurity, per the Federal Register (Document 2024-30983, 90 FR 898). This 125-page proposal (45 CFR Parts 160 and 164) emphasizes risk assessments, multi-factor authentication (MFA), encryption, and alignment with HITRUST or SOC 2 Type II. Comments close March 7, 2025. Notably, 97% of AI security incidents lacked access controls, per IBM's 2024 findings.
HIPAA violations can cost up to $50,000 per incident, with healthcare facing amplified fines due to PHI's sensitivity. Always verify a provider's BAA before migrating data to avoid criminal penalties and multimillion-dollar breaches.
Essential Features of HIPAA-Compliant Cloud Storage for 2025
Selecting HIPAA-compliant cloud storage for healthcare demands more than storage volume—prioritize Security Rule alignment and 2025 digital health demands. Target certifications like HITRUST or FedRAMP, backed by 4.5+ star ratings on G2 and Capterra.
Encryption Priorities: Demand AES-256 end-to-end for data at rest and transit, with customer-managed keys through key management systems (KMS) to prevent vendor access, as detailed in our Client-Side vs Server-Side Encryption: Pros & Cons 2025 guide, which weighs options for HIPAA-level protection against breaches and quantum threats. Stolen credentials fueled 16% of breaches (292 days resolution), making this vital.
Access Management: Enforce least privilege via role-based access control (RBAC). Integrate MFA and zero-trust for every access point. Phishing drills and just-in-time access mitigate 15% credential-theft breaches.
Monitoring and Compliance: Immutable audit logs track actions with real-time alerts. Automated reports aid audits, as 2024 breaches averaged 258 days.
Data Location and Resilience: Opt for U.S.-based storage for compliance and low-risk transfers. Include automated backups, versioning, and disaster recovery (e.g., <1-hour recovery point objective). Shadow data hit 40% of breaches—ensure hybrid oversight.
Seamless Integration: Seek EHR-compatible APIs (e.g., Epic, Cerner) for syncing, plus auto-scaling for telemedicine peaks. In 2025, AI shines: threat detection and automation cut breach costs by $2.2 million, speeding identification by 98 days.
Choose user-friendly interfaces, round-the-clock support, and clear pricing. Hyperscalers suit enterprises; niche tools fit small practices.

Encryption Standards
AES-256 end-to-end for data at rest and in transit, with customer-managed keys to thwart unauthorized access.
Access Controls
RBAC, MFA, and zero-trust architecture to combat 16% of breaches from stolen credentials.
Audit Trails
Immutable logging and AI alerts for faster detection, reducing breach costs by up to $2.2 million.
Data Residency
U.S.-centric storage with backups to mitigate shadow data risks in 40% of hybrid breaches.
Integration
EHR compatibility via APIs for scalable telemedicine in 2025.
AI Threat Detection
ML models that cut identification times by 98 days, essential for HIPAA's evolving rules.
Top 5 HIPAA-Compliant Cloud Storage Providers for Healthcare in 2025
Our picks draw from 2025 analyses, G2/Capterra scores (4.5+ average), and features like AI defenses against HHS-proposed rules. All offer BAAs, HITRUST, and robust PHI protection.
1. Microsoft Azure for Healthcare: Versatile HIPAA-Compliant Storage
Azure's HIPAA-compliant platform via Azure for Health excels in EHR hosting and AI analytics, ensuring U.S. data control.
Standout Features: Azure Information Protection for labeling/encryption; Microsoft 365 for collaboration. BAA spans 100+ services; Azure Sentinel's ML spots anomalies—AI security saved $1.93 million per 2024 breach. 2025 zero-trust enhancements match HHS updates.
Pros: Enterprise customization; top scalability. Cons: Learning curve for small teams. Starts at $0.02/GB/month (blob storage), pay-as-you-go.
2. Amazon Web Services (AWS) HIPAA-Eligible Services: Scalable Medical Data Storage
AWS dominates with S3 for encrypted, 99.999999999% durable storage—perfect for big hospitals.
Key Advantages: KMS encryption; HITRUST centers. AWS Config automates audits against misconfigurations (15% breaches). 2025 GuardDuty AI accelerates phishing detection by 98 days. BAAs for eligible services.
Pros: Reliability at scale; strong APIs. Cons: Setup complexity; costs for novices. ~$0.023/GB/month standard.
3. Google Cloud Platform (GCP) for Healthcare: AI-Powered PHI Storage
GCP leads in AI storage with secure buckets for PHI, ideal for genomics/telemedicine.
Benefits: BigQuery ML for predictions; auto-encryption; free BAAs. Chronicle anomalies address 63% AI governance gaps. 2025 U.S. residency boosts HHS compliance.
Pros: Analytics innovation; efficient pricing. Cons: Best in Google ecosystem; less intuitive. $0.02/GB/month, discounts available.
4. Box for Healthcare: Collaborative HIPAA-Compliant File Sharing
Box's HIPAA edition focuses on secure sharing for clinic workflows.
Highlights: RBAC; Box Sign e-signatures; Epic integration. 2025 AI classifies PHI to curb shadow data.
Pros: Non-IT friendly; governance tools. Cons: Not for huge archives. Business Plus: $15/user/month.
5. Datto: Affordable HIPAA Cloud Storage for Small Practices
Datto (Kaseya) delivers compliance-focused storage for mid-sized providers, aligning with needs for smaller operations as highlighted in our Best Secure Cloud Storage for Small Businesses 2025 overview, which covers encryption and compliance for budget-conscious teams.
Strengths: Ransomware-resistant backups; easy EHR links. 2025 AI monitoring aids understaffed teams (shortages up 26%, adding $1.76M costs). Standard BAAs/U.S. centers.
Pros: Fast setup; healthcare-centric. Cons: Less hyperscaler flexibility. $10–$20/user/month.
Honorable Mentions: Dropbox Business (simple BAA sharing); Oracle Cloud (analytics); IBM Cloud (hybrids).
Head-to-Head Comparison: Best HIPAA-Compliant Cloud Storage Options 2025
This table compares top providers on 2025 HIPAA criteria, based on reviews and alignments.
| Criterion | Azure | AWS | GCP | Box | Datto |
|---|---|---|---|---|---|
| Pricing (per GB/month or equiv.) | $0.02 | $0.023 | $0.02 (tiered) | $15/user | $10–$20/user |
| Encryption Level | AES-256, KMS | AES-256, KMS | AES-256, Auto | AES-256, At-Rest | AES-256, Immutable |
| Storage Limits | Unlimited, Scalable | Unlimited | Unlimited | Unlimited (Enterprise) | Up to Petabytes |
| Access Controls | RBAC, MFA, Zero-Trust | RBAC, MFA, IAM | RBAC, MFA, BeyondCorp | RBAC, MFA | RBAC, MFA |
| Ease of Use (G2 Rating) | 4.5/5 | 4.4/5 | 4.6/5 | 4.7/5 | 4.3/5 |
| Customer Support | 24/7 Enterprise | 24/7 Premier | 24/7 Dedicated | 24/7 Phone/Chat | 24/7 U.S.-Based |
| AI Threat Detection | Yes (Sentinel) | Yes (GuardDuty) | Yes (Chronicle) | Basic | Yes (Monitoring) |
| HIPAA Certifications | HITRUST, SOC 2 | HITRUST, FedRAMP | HITRUST, SOC 2 | HITRUST | SOC 2, HIPAA BAA |
Azure/GCP excel in AI; Box in usability; AWS in scale; Datto in budget.
Implementation Guide and 2025 Trends for Secure Cloud Storage
Begin with risk assessments: Map PHI, detect shadow data, pilot setups. Lock in BAAs, enforce MFA training, and audit yearly. For 2025, deploy AI for 98-day-faster threat spotting and HHS-compliant automation.
Emerging Trends: - Quantum-resistant encryption and blockchain audits - Multi-cloud to avoid vendor lock-in, but DSPM for 15% misconfiguration risks - By 2026, AI risk mandates in HIPAA—report to law enforcement for 20% cost cuts
In 2025, choose Azure for large ops, Datto for small—balance security with cloud gains for PHI protection.
"Organizations leveraging AI extensively in security operations saved an average of $1.93 million per breach, reducing lifecycle by 108 days through faster detection and automated responses."
Ready to Secure Your Healthcare Data?
Evaluate your needs with a free HIPAA compliance checklist and explore top providers using our Cloud Comparison Tool, which helps filter HIPAA-eligible options by price and features to match your storage requirements. Contact experts today for tailored 2025 recommendations.
View Comparison | Learn More on HHSFull video transcript
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There's no such thing as
a HIPAA certified cloud.
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The government doesn't certify anyone.
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00:00:05,099 --> 00:00:08,166
What counts is a contract
you sign with the provider,
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00:00:08,206 --> 00:00:12,720
called a business associate agreement,
before the first patient file goes in.
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00:00:14,239 --> 00:00:16,503
Start with the people who enforce HIPAA.
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00:00:16,543 --> 00:00:19,671
This is the US Department of
Health and Human Services.
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00:00:19,711 --> 00:00:22,880
And this is its own answer
to the certificate question.
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00:00:24,194 --> 00:00:25,489
The question is simple.
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Does a practice have to certify that
it follows HIPAA's security rules?
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00:00:30,021 --> 00:00:35,191
The answer is no. There is no rule
that says anyone has to be certified.
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00:00:35,231 --> 00:00:41,236
So there is no official HIPAA certificate.
Not for a practice, and not for a cloud.
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00:00:42,599 --> 00:00:44,708
And a few lines down, it goes further.
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The department doesn't recognize
private certifications either.
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A badge bought from a company that sells
HIPAA certificates doesn't change what the
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law asks of you.
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00:00:55,287 --> 00:01:00,024
Now a cloud company. This is
Dropbox's own help page about HIPAA.
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00:01:00,429 --> 00:01:05,827
And Dropbox says the same thing about
itself. There is no official certification.
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00:01:05,867 --> 00:01:09,049
So when you see a cloud
sold as HIPAA certified,
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00:01:09,089 --> 00:01:11,774
nobody in government gave it that title.
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00:01:13,203 --> 00:01:16,361
So what does count? Back
to the health department.
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This is its guidance on cloud computing.
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00:01:19,374 --> 00:01:22,532
When a cloud company stores
patient information for you,
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the law calls it a business associate.
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That just means a company that handles
patient information on your behalf.
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And with a business associate, you must
sign a business associate agreement.
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You'll see it shortened to B A A.
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It's a contract, and it's the
thing that actually counts.
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Here's what that contract does.
On one side is your practice.
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You sign it before the
first patient file goes in,
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and you decide who gets to see what.
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On the other side is the cloud company.
It promises to protect the information.
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To use it only the way
the agreement allows.
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And to report breaches and
security incidents back to you.
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00:02:03,696 --> 00:02:06,043
And if you skip it? The guidance is blunt.
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Keep patient information with a
cloud company without that agreement,
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and you are in violation of HIPAA.
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This isn't theoretical.
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The department settled with a practice
that kept records on over three thousand
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people on a cloud server,
with no agreement in place.
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00:02:23,584 --> 00:02:25,469
Now the question people ask next.
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What if the files are encrypted, and the
cloud company doesn't even have the key?
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That's the zero-knowledge setup,
where only you can unlock your files.
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The answer is yes, it's
still a business associate.
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Not having the key doesn't get it out of
the rules. You still need the agreement.
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And here's why. Encryption
stops people reading your files.
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It doesn't stop them being
corrupted by malware,
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or being out of reach in an emergency.
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The law cares about all of that.
So zero-knowledge is good to have.
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It just isn't a pass.
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00:03:01,702 --> 00:03:06,792
So which clouds will sign one, and on which
plans? We'll start with Google's page.
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Google is clear.
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00:03:08,217 --> 00:03:10,578
If you haven't signed its agreement,
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you must not put patient
information in its services at all.
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That includes Google Drive.
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00:03:17,745 --> 00:03:21,936
And look who signs it. An administrator,
in Google's admin console.
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00:03:21,976 --> 00:03:25,346
That's a Google Workspace
account, a business account.
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A personal Google account has no administrator,
so there's no agreement to accept.
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Back to Dropbox, at the
top of the same page.
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Read who this page is for. Teams on Dropbox
Standard, Advanced, Business, and up.
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These are team plans. The personal
plans aren't on the list.
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And the timing matters.
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The agreement has to be in place before
you move any patient information in.
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Not after.
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Dropbox also says the rest is on you.
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Ultimately, it's up to you to
make sure you're complying.
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The agreement covers Dropbox's
side, not your settings.
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00:04:05,134 --> 00:04:10,455
And one easy miss. Apps you connect to
Dropbox aren't covered by its agreement.
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Each one needs checking on its own.
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Now Sync.com, a privacy-focused cloud.
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Sync names its plans. Three Pro Solo
plans, and every Pro Teams plan.
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00:04:23,504 --> 00:04:27,285
If your plan isn't on this
list, it doesn't include it.
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00:04:28,597 --> 00:04:30,123
And notice the order.
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Sync signs the agreement on request,
once you've bought one of those plans.
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So, buy the right plan first. Then ask.
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Sync's page has a setup tip too.
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When you share patient files with a link,
always set a password and an expiry date.
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Again, that part is your job.
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Last, Proton Drive.
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Its answer sits in the FAQ at the
bottom of its healthcare page.
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Proton is the odd one out. It says it
offers the agreement to all users.
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00:05:02,761 --> 00:05:08,038
You still have to ask for a signed copy,
by email. It doesn't happen on its own.
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00:05:10,000 --> 00:05:14,900
So, here's what to take away. There's no
such thing as a HIPAA certified cloud.
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00:05:14,940 --> 00:05:17,777
What counts is a business
associate agreement,
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00:05:17,817 --> 00:05:20,591
signed before the first
patient file goes in.
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00:05:20,631 --> 00:05:24,968
Check that your plan offers one,
because personal plans usually don't.
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Encryption doesn't replace it,
even when only you hold the key.
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00:05:28,948 --> 00:05:31,910
And once it's signed, the
settings are your job.
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Which providers sign one, and on which
plans, is on the page linked below.
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Everything here comes from the
official pages. It's not legal advice.